Hydrochloric Acid → HCID 178429222, compound

Participants

Reaction Steps

240 mg. (3.5 mMole) sodium nitrite were added portionwise to a suspension of 570 mg. (3 mMole) 5,6-diamino-3,3-dimethylindolin-2-one in 6 ml. 1N hydrochloric acid, the temperature being maintained between 0° and 5° C. by ice cooling. A red solution is obtained which is heated to 50° to 60° C. for 5 minutes. After cooling to ambient temperature, the crystalline precipitate obtained is filtered off with suction and washed with water. There are obtained 380 mg. of the title compound in the form of red crystals; m.p. 288°-291° C. (decomp.).

Provenance & Evidence