Ammonium thiocyanate → HCID 85533506, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 3.8 g (50 mM) of ammonium thiocyanate in 100 ml of acetonitrile containing 7.8 g (50 mM) of phenyl chloroformate was stirred at 24° C. for one hour. The reaction mixture was filtered into a suspension of 6.88 g (50 mM) of 2-amino-1,3,4-thiadiazole hydrochloride in 75 ml of acetonitrile and 25 ml of propylene oxide. The reaction mixture was stirred for two hours at 24° C. and then filtered to provide a solid precipitate identified as 6.42 g of [(1,3,4-thiadiazol-2-ylamino)thioxomethyl carbamic acid, phenyl ester.

Provenance & Evidence