反应详情

was prepared in 89% yield from 24.4 g (0.14 mol) of 4-amino-2,6-dichlorophenol, 18.1 g (0.15 mol) of N,N-dimethylaniline and 28.8 g (0.14 mol) of 6-bromohexanoyl chloride according to the procedure of Example 6, part a, except that the reaction was cooled on ice during the addition and was stirred at room temperature rather than refluxed. The product was crystallized from ethanol-water, mp 113°-114° C.

1. temperaturewas cooled on ice during the addition
2. temperaturethan refluxed
3. customThe product was crystallized from ethanol-water, mp 113°-114° C.