Acetic Anhydride → HCID 20039786, compound

HRID 1762918Notes

Reaction equation

[O:1]([CH2:8][CH:9]([CH:11]1[CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][NH:12]1)[OH:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:18](OC(=O)C)(=O)[CH3:19]>>[CH2:18]([N:12]1[CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH:11]1[CH:9]([CH2:8][O:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)[OH:10])[CH3:19]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 20039778HCID 20039778, compound

Product 1

HCID 20039786HCID 20039786, compound

Procedure

The free base of the title compound is prepared by reacting α-phenoxymethyl-2-homopiperidinemethanol with acetic anhydride and following the procedure of Example 12.

Sources & evidence

ORD record: ord-c534622ec8e84c6bad8c9e56b281f476
Source dataset: uspto-grants-1989_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04835164

Reaction notes

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