HuagongsheHuagongshe Chemistry Print Report · For research reference only
Butyl 7-(benzyloxy)-1H-indole-2-carboxylate → Butyl 7-hydroxy-1H-indole-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Butyl 7-(benzyloxy)-1H-indole-2-carboxylate | HCID 13242198 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Butyl 7-hydroxy-1H-indole-2-carboxylate | HCID 13093609 | 76.5% |
Reaction Steps
Under the conditions of Example 14(C), a solution of 5.8 g of 7-benzyloxyindole-2-carboxylic acid n-butyl ester in 200 ml of methanol is hydrogenated and worked up, thus obtaining 3.2 g of 7-hydroxyindole-2-carboxylic acid n-butyl ester, mp 150°-151° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04835175 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-a0833b45fd764463851a326b4f2aff61 |
| Source note | uspto-grants-1989_05 |