HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 13243481, compound → HCID 13243474, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 13243481 | HCID 13243481 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 13243474 | HCID 13243474 | 68.3% |
Reaction Steps
229 mg of 2-(N-benzyl-N-tert-butylamino)-1-(7-benzyloxy-2-hydroxymethylindol-4-yl)ethanol is hydrogenated in 10 ml of methanol for 10 minutes in the presence of 40 mg of 10% palladium-carbon, filtered, the filtrate concentrated and recrystallized from ethanol/diisopropyl ether, yielding 95 mg of 2-(N-tert-butylamino)-1-(7-hydroxy-2-hydroxymethylindol-4-yl) ethanol, mp 150° C. (decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04835175 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-22cfb752ac024da5b94798b0630cf1ee |
| Source note | uspto-grants-1989_05 |