HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,1-Dimethylhydrazine → 3-Ethyl 5-methyl 6-(chlorodifluoromethyl)-4-(2,2-dimethylhydrazino)-2-(trifluoromethyl)-3,5-pyridinedicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,1-Dimethylhydrazine | HCID 5976 | — |
| Reactant | 3-Ethyl 5-methyl 4-chloro-6-(chlorodifluoromethyl)-2-(trifluoromethyl)-3,5-pyridinedicarboxylate | HCID 14013759 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Ethyl 5-methyl 6-(chlorodifluoromethyl)-4-(2,2-dimethylhydrazino)-2-(trifluoromethyl)-3,5-pyridinedicarboxylate | HCID 14013808 | 83.8% |
Reaction Steps
This compound was prepared as described in Example 37: 5.0 g (0.013 mol) of product of Example 28, 1.9 ml (0.025 mol) of unsym-dimethylhydrazine in 30 ml of DMF were reacted affording a residue which was recrystallized in hot hexane to give 4.57 g (83.8%) of product as a yellow solid; mp 97°-98° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04835279 |
| Source dataset | uspto-grants-1989_05 |
| ORD ID | ord-e6d9ef5adb744dfd97621b54d94c23d7 |
| Source note | uspto-grants-1989_05 |