Acetone → HCID 20309765, compound

Participants

Reaction Steps

10 ml. of ICH3 are slowly added to a solution of 10 g. of 3,4,5-trimethoxyphenyl-(4-methyl-2-pyridyl) carbinol in 125 ml. of anhydrous acetone and 15 ml. of anhydrous benzene. The resulting mixture is agitated for 1 hour at room temperature, then refluxed for 2 hours, then left to cool, 13.04 g being obtained, with an 87% yield, of a crystalline precipitate identifiable as 3,4,5-trimethoxyphenyl-(1,4-dimethyl-2-pyridinyl)-carbinol iodide. A sample recrystallized from ethanol has a melting point of 162°-163.5° C.

Provenance & Evidence