Epibromohydrin → HCID 20309544, compound

HRID 1763304Notes

Reaction equation

[OH:1][C:2]1[CH:15]=[C:14]([CH3:16])[CH:13]=[CH:12][C:3]=1[C:4]([CH2:6][CH2:7][C:8]([O:10][CH3:11])=[O:9])=[O:5].[CH2:17]([CH:19]1[O:21][CH2:20]1)Br>>[O:21]1[CH2:20][CH:19]1[CH2:17][O:1][C:2]1[CH:15]=[C:14]([CH3:16])[CH:13]=[CH:12][C:3]=1[C:4]([CH2:6][CH2:7][C:8]([O:10][CH3:11])=[O:9])=[O:5]

Participants

Reactant 2

HCID 18430Epibromohydrin

HCID 14107496HCID 14107496, compound

Product 1

HCID 20309544HCID 20309544, compound

Procedure

Methyl 3-(2-hydroxy-4-methylbenzoyl)propionate was reacted with epibromohydrin in a similar manner to the procedure described in Example 1(ii) to give methyl 3-[2-(2,3-epoxypropoxy)-4-methylbenzoyl]propionate, m.p. 61.5°-63°.

Sources & evidence

ORD record: ord-466eeeff25eb4d6fa68d828f05cb1e69
Source dataset: uspto-grants-1978_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04111936

Reaction notes

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