HCID 20309585, compound → HCID 20309520, compound

HRID 1763315Notes

Reaction equation

HRID 1763315 reaction equation
[C:1]([NH:5][CH2:6][CH:7]([OH:25])[CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]#[N:17])=[CH:12][C:11]=1[C:18]1[CH2:19][CH2:20][C:21](=[O:24])[NH:22][N:23]=1)([CH3:4])([CH3:3])[CH3:2]>C(O)CCC>[C:1]([NH:5][CH2:6][CH:7]([OH:25])[CH2:8][O:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]#[N:17])=[CH:12][C:11]=1[C:18]1[CH:19]=[CH:20][C:21](=[O:24])[NH:22][N:23]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 20309585HCID 20309585, compound

Product 1

HCID 20309520HCID 20309520, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture of 6-[2-(3-t-butylamino-2-hydroxypropoxy)-5-cyanophenyl]-4,5-dihydro-3(2H)-pyridazinone and chloramil was heated under reflux in n-butanol to give 6-[2-(3-t-butylamino-2-hydroxypropoxy)-5-cyanophenyl]-3(2H)-pyridazinone.

Workup

  1. temperaturewas heated

Sources & evidence

ORD record
ord-8ec55f8d030e472581ff6801362cd570
Source dataset
uspto-grants-1978_09
Patent number
US04111936

Reaction notes

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