Succinic anhydride → HCID 20309554, compound
Reaction equation
[OH:1][C:2]1[CH:10]=[CH:9][C:5]([CH2:6][C:7]#[N:8])=[CH:4][CH:3]=1.[C:11]1(=[O:17])[O:16][C:14](=[O:15])[CH2:13][CH2:12]1.[Cl-].[Al+3].[Cl-].[Cl-]>>[C:7]([CH2:6][C:5]1[CH:4]=[CH:3][C:2]([OH:1])=[C:10]([CH:9]=1)[C:11]([CH2:12][CH2:13][C:14]([OH:16])=[O:15])=[O:17])#[N:8]Participants
4
Procedure
4-Hydroxybenzyl cyanide was reacted with succinic anhydride and aluminium chloride in a similar manner to that described in Example 11 (i) to give 3-(5-cyanomethyl-2-hydroxybenzoyl)-propionic acid.
Sources & evidence
- ORD record
- ord-253b7be584144fb48bd91e2e8cfd2c2a
- Source dataset
- uspto-grants-1978_09
- Patent number
- US04111936
Reaction notes
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