Acetic Anhydride → HCID 20309478, compound

HRID 1763324Notes

Reaction equation

[C:1](OC(=O)C)(=[O:3])[CH3:2].[NH2:8][C:9]1[CH:10]=[CH:11][C:12]([O:22][CH2:23][CH:24]([OH:31])[CH2:25][NH:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[C:13]([C:15]2[CH:16]=[CH:17][C:18](=[S:21])[NH:19][N:20]=2)[CH:14]=1>>[C:1]([NH:8][C:9]1[CH:10]=[CH:11][C:12]([O:22][CH2:23][CH:24]([OH:31])[CH2:25][NH:26][C:27]([CH3:28])([CH3:30])[CH3:29])=[C:13]([C:15]2[CH:16]=[CH:17][C:18](=[S:21])[NH:19][N:20]=2)[CH:14]=1)(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 7918Acetic Anhydride

HCID 20309493HCID 20309493, compound

Product 1

HCID 20309478HCID 20309478, compound

Procedure

Addition of acetic anhydride to a stirred suspension of 6-[5-amino-2-(3-t-butylamino-2-hydroxypropoxy)phenyl]-3(2H)-pyridazinethione in an aqueous buffer solution at pH 5.5 gave 6-[5-acetamido-2-(3-t-butylamino-2-hydroxypropoxy)phenyl]-3-(2H)-pyridazinethione.

Sources & evidence

ORD record: ord-1e24ad46bd124587819441b21b2ea88e
Source dataset: uspto-grants-1978_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04111936

Reaction notes

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