Epibromohydrin → HCID 20309540, compound

HRID 1763331Notes

Reaction equation

[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([OH:16])=[C:6]([CH:15]=1)[C:7]([CH2:9][CH2:10][C:11]([O:13][CH3:14])=[O:12])=[O:8].[CH2:17]([CH:19]1[O:21][CH2:20]1)Br>>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([O:16][CH2:17][CH:19]2[O:21][CH2:20]2)=[C:6]([CH:15]=1)[C:7]([CH2:9][CH2:10][C:11]([O:13][CH3:14])=[O:12])=[O:8]

Participants

Reactant 2

HCID 18430Epibromohydrin

HCID 14452845HCID 14452845, compound

Product 1

HCID 20309540HCID 20309540, compound

Procedure

Methyl 3-(5-methyl-2-hydroxybenzoyl)propionate was reacted with epibromohydrin in a similar manner to the procedure described in Example 1(ii) to give methyl 3-[5-methyl-2-(2,3-epoxypropoxy)benzoyl]propionate as an oil.

Sources & evidence

ORD record: ord-c12d1b8245fe4609b8d4f5c487581d00
Source dataset: uspto-grants-1978_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04111936

Reaction notes

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