HCID 19096124, compound → 4-Phenoxy-3-sulfamoylbenzoic acid

HRID 1763383Notes

Reaction equation

HRID 1763383 reaction equation
C[O:2][C:3](=[O:21])[C:4]1[CH:9]=[C:8]([S:10](=[O:13])(=[O:12])[NH2:11])[C:7]([O:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:6][CH:5]=1>[OH-].[Na+]>[O:14]([C:7]1[C:8]([S:10](=[O:13])(=[O:12])[NH2:11])=[CH:9][C:4]([C:3]([OH:21])=[O:2])=[CH:5][CH:6]=1)[C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1

Participants

3

Reactant 1

HCID 19096124HCID 19096124, compound

Product 1

HCID 203345274-Phenoxy-3-sulfamoylbenzoic acid

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

6.2 g of 3-N-(3-azabicyclo-[3.2.0]-heptano)-4-phenoxy-5-sulphamylbenzoic acid methyl ester are suspended in 60 ml of 1 N NaOH and the suspension is heated on the waterbath until a clear solution is formed. The acid is then precipitated with 2 N HCl, while stirring well, and is recrystallised from glacial acetic acid.

Workup

  1. temperaturethe suspension is heated on the waterbath until a clear solution
  2. customis formed
  3. customThe acid is then precipitated with 2 N HCl
  4. customis recrystallised from glacial acetic acid

Sources & evidence

ORD record
ord-5b47d70dcdd749a2b2db0a096a253e8a
Source dataset
uspto-grants-1978_09
Patent number
US04111953

Reaction notes

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