Lithium oxalate → HCID 86735988, compound

HRID 1763393Notes

Reaction equation

HRID 1763393 reaction equation
C([O-])(=O)[C@@H](C(CO)(C)C)[OH:3].[Ca+2].[C:12]([O-:21])(=[O:20])[C@@H:13]([C:15]([CH2:18][OH:19])([CH3:17])[CH3:16])[OH:14].C([O-])(=O)C([O-])=O.[Li+:28].[Li+]>O>[OH2:3].[C:12]([O-:21])(=[O:20])[C@@H:13]([C:15]([CH2:18][OH:19])([CH3:17])[CH3:16])[OH:14].[Li+:28]

Participants

4

Reactant 2

HCID 68383Lithium oxalateHCID 12876781HCID 12876781, compound

Product 1

HCID 86735988HCID 86735988, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A slurry of 334 grams of DL-calcium pantoate and 102 grams of lithium oxalate in 600 grams of water was heated at boiling temperature with continuous stirring in the apparatus described in Example 1 for 4 hours. The resulting mixture was then filtered while hot and the calcium oxalate that was thus separated was washed three times with 70-milliliter portions of hot water. The filtrate and wash waters were then combined and evaporated in a rotary vacuum evaporator to a volume of 400 milliliters during which 254 grams of DL-lithium pantoate monohydrate having a melting point of 107°-110° C, equivalent to 74% of the theoretical yield, separated and was collected. From the mother liquor by further concentration, DL-lithium pantoate monohydrate, in an amount equivalent to 20% of the original DL-pantolactone, was recovered.

Workup

  1. filtrationThe resulting mixture was then filtered while hot and the calcium oxalate that
  2. customwas thus separated
  3. washwas washed three times with 70-milliliter portions of hot water
  4. washThe filtrate and wash waters
  5. customevaporated in a rotary vacuum evaporator to a volume of 400 milliliters during which 254 grams of DL-lithium pantoate monohydrate having a melting point of 107°-110° C
  6. customequivalent to 74% of the theoretical yield, separated
  7. customwas collected
  8. concentrationFrom the mother liquor by further concentration, DL-lithium pantoate monohydrate
  9. customin an amount equivalent to 20% of the original DL-pantolactone, was recovered

Sources & evidence

ORD record
ord-fa305c4cd55d41a7ac2a3b3fb8f4af10
Source dataset
uspto-grants-1978_09
Patent number
US04111987

Reaction notes

Loading…