1-Methylpiperazine → HCID 54542539, compound

Participants

Reaction Steps

N-methylpiperazine (2 g) is dissolved in 20 ml benzene and reacted with a solution of 4.5 g 2,2,2-trichloroethyl chloroformate in 20 ml benzene, with stirring and cooling in an ice bath. After stirring for 2 hours the resulting crystals are collected by vacuum filtration, washed with ether and dried under water-pump vacuum at room temperature, to give the hydrochloride of the title compound, m.p. 238°-240° C.

Provenance & Evidence