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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1763469Generated: October 31, 2026

7-Aminocephalosporanic acid → HCID 178476912, compound

https://huagongshe.com/reaction/1763469

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Aminocephalosporanic acidHCID 441328—
ReactantSodium BicarbonateHCID 516892—
ReactantHCID 178476915HCID 178476915—
ReactantHCID 178527083HCID 178527083—
ProductHCID 178476912HCID 178476912—
ProductHCID 178511755HCID 178511755—

Reaction Steps

Reaction of 7-aminocephalosporanic acid with 1-diethoxyphosphinylmethyltetrazole-5-thiol and 1-phosphonomethyltetrazole-5-thiol in the presence of 1 and 3 molecular equivalents of sodium bicarbonate, respectively, as described in Example 10 gives 7β-amino-3-(1-diethoxyphosphinylmethyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid and 7β-amino-3-(1-phosphono-methyltetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid, respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04112086
Source datasetuspto-grants-1978_09
ORD IDord-f1e05e89c7584b18babcf5e4fb76e81f
Source noteuspto-grants-1978_09