HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Diethoxyphosphorylethyl)isoindole-1,3-dione → Diethyl (2-aminoethyl)phosphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Diethoxyphosphorylethyl)isoindole-1,3-dione | HCID 254377 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Product | Diethyl (2-aminoethyl)phosphonate | HCID 2733596 | — |
Reaction Steps
A mixture of 4.67 g (0.015 mol) of diethyl phthalimidoethylphosphonate in 30 ml of ethanol and 1.2 ml of 100% hydrazine hydrate is kept at ambient temperature for ca. 16 hours then is refluxed for 2 hours. The mixture is cooled and filtered and the filtrate is concentrated to give diethyl (2-aminoethyl)phosphonate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112086 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-270cbcc80b03476a9e0e327c0e5b21bc |
| Source note | uspto-grants-1978_09 |