Acetic Acid → HCID 136308665, compound

HRID 1763516Notes

Reaction equation

HRID 1763516 reaction equation
CC1[CH:3]=[N:4][N:5]2[C:14]=1[C:13]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[NH:7][C:6]2=[O:15].S(=O)(=O)(O)O.[Cr](O)(O)(=O)=O.[C:26]([OH:29])(=[O:28])[CH3:27]>O>[C:27]1([C:26]([OH:29])=[O:28])[CH:3]=[N:4][N:5]2[C:14]=1[C:13]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[NH:7][C:6]2=[O:15]

Participants

6

Reactant 4

HCID 176Acetic Acid2×HCID 1118Sulfuric AcidHCID 24425Chromic AcidHCID 135737569HCID 135737569, compound

Product 1

HCID 136308665HCID 136308665, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To 40 g (0.19 mole) of 1-methyl-pyrazolo[1,5-c]quinazolin-5(6H)-one in a rapidly stirring mixture of 350 g of concentrated sulfuric acid and 100 g of acetic acid is added, dropwise a solution of 100 g of chromic acid in 175 g water and 50 g acetic acid. After 12 hours, the reaction is poured into 2 l. of ice water. The reaction mixture is concentrated, cooled and the title compound filtered off and dried.

Workup

  1. additionis added
  2. additionthe reaction is poured into 2 l
  3. concentrationThe reaction mixture is concentrated
  4. temperaturecooled
  5. filtrationthe title compound filtered off
  6. customdried

Sources & evidence

ORD record
ord-2bf8ddb791e847e7b9cd95280d0a158e
Source dataset
uspto-grants-1978_09
Patent number
US04112096

Reaction notes

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