HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 5-(4-Fluorobenzoyloxy)-3-methyl-4-phenyl-1-(alpha-methyl-3,4-dichlorobenzyl)-pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | 3-Methyl-4-phenyl-1-(alpha-methyl-3,4-dichlorobenzyl)-5-pyrazolone | HCID 20335894 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 5-(4-Fluorobenzoyloxy)-3-methyl-4-phenyl-1-(alpha-methyl-3,4-dichlorobenzyl)-pyrazole | HCID 20335859 | — |
Reaction Steps
0.1 mol (34.7 g) of 3-methyl-4-phenyl-1-(α-methyl-3,4-dichlorobenzyl)-5-pyrazolone was dissolved in 300 ml of absolute dioxane. After adding 15 ml of triethylamine, 0.11 mol (17 g) of p-fluorobenzoyl chloride in dioxane was added dropwise. After heating for several hours under reflux, the reaction batch was worked up as follows.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112109 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-dd297b95e2ab4610a6ffe85fbfa5bfdf |
| Source note | uspto-grants-1978_09 |