HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → 6-(m-Acetamidophenyl)-1,2,4-triazolo[4,3-b]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3-([1,2,4]Triazolo[4,3-b]pyridazin-6-yl)aniline | HCID 12726867 | — |
| Product | 6-(m-Acetamidophenyl)-1,2,4-triazolo[4,3-b]pyridazine | HCID 7532146 | — |
Reaction Steps
A mixture of 1.0 g. of g. of 6-(m-aminophenyl)-1,2,4-triazolo[4,3-b]pyridazine (prepared as in Example 26) and 4 ml. of acetic anhydride is left at room temperature for 2 hours and then is triturated with ether and filtered. The insoluble material is recrystallized from ethyl alcohol to afford yellow crystals of 6-(m-acetamidophenyl)-1,2,4-triazolo[4,3-b]pyridazine, m.p. 248°-250° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112095 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-734653469e8441e39226092c9b628f67 |
| Source note | uspto-grants-1978_09 |