HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetohydrazide → 6-(2-Fluorophenyl)-3-methyl-1,2,4-triazolo[4,3-b]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetohydrazide | HCID 14039 | — |
| Reactant | 3-Chloro-6-(2-fluorophenyl)pyridazine | HCID 12449555 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 6-(2-Fluorophenyl)-3-methyl-1,2,4-triazolo[4,3-b]pyridazine | HCID 12726823 | — |
Reaction Steps
As in Example 36, a mixture of 2.5 g. of 3-chloro-6-(o-fluorophenyl)-pyridazine and 1.76 g. of acetylhydrazine in 50 ml. of n-butanol is refluxed for 48 hrs. to give 2.0 g. of product as off-white crystals, m.p. 147°-149° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112095 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-e33034c14a694ea8907693d91868e635 |
| Source note | uspto-grants-1978_09 |