Acetohydrazide → HCID 12726822, compound

HRID 1763605Notes

Reaction equation

HRID 1763605 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]([F:14])[CH:9]=2)=[CH:6][CH:7]=1.[C:15]([NH:18][NH2:19])(=O)[CH3:16]>C(O)CCC>[CH3:16][C:15]1[N:3]2[N:4]=[C:5]([C:8]3[CH:13]=[CH:12][CH:11]=[C:10]([F:14])[CH:9]=3)[CH:6]=[CH:7][C:2]2=[N:19][N:18]=1

Participants

4

Reactant 2

HCID 14039AcetohydrazideHCID 12449556HCID 12449556, compound

Product 1

HCID 12726822HCID 12726822, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

As in Example 36, a mixture of 3.0 g. of 3-chloro-6-(m-fluorophenyl)pyridazine, 2.14 g. of acetylhydrazine and 50 ml. of n-butanol is refluxed 48 hrs. to give 2.0 g. of the product as crystals, m.p. 184°-186° C.

Workup

  1. additionAs in Example 36, a mixture of 3.0 g
  2. customto give 2.0 g

Sources & evidence

ORD record
ord-ebb92ab770834f8191463ee19ba5741d
Source dataset
uspto-grants-1978_09
Patent number
US04112095

Reaction notes

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