Acetohydrazide → HCID 20310378, compound

HRID 1763627Notes

Reaction equation

HRID 1763627 reaction equation
ClC1C(Cl)=CC=CC=1C=O.Cl[C:12]1[N:13]=[N:14][C:15]([C:18]2[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:19]=2[Cl:25])=[CH:16][CH:17]=1.[C:26]([NH:29][NH2:30])(=O)[CH3:27]>C(O)CCC>[CH3:27][C:26]1[N:13]2[N:14]=[C:15]([C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([Cl:24])[C:19]=3[Cl:25])[CH:16]=[CH:17][C:12]2=[N:30][N:29]=1

Participants

5

Reactant 3

HCID 14039AcetohydrazideHCID 357452,3-DichlorobenzaldehydeHCID 20310375HCID 20310375, compound

Product 1

HCID 20310378HCID 20310378, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

As described in Example 35, 2,3-dichlorobenzaldehyde is converted to 3-chloro-6-(2,3-dichlorophenyl)pyridazine. A mixture of this compound and acetic acid hydrazide in n-butanol is refluxed for 24 hours to give the product of the example.

Workup

  1. temperatureis refluxed for 24 hours
  2. customto give the product of the example

Sources & evidence

ORD record
ord-d97dcd89852f4d509938fdd8ab47b775
Source dataset
uspto-grants-1978_09
Patent number
US04112095

Reaction notes

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