Dichloromethane → HCID 13154188, compound

Participants

Reaction Steps

A solution of 35 mg. cis-2-carboxy-4-cyano-N-styrylpyrrole in 0.5 ml. of dry methylene chloride was treated with 45 μl. of trifluoroacetic anhydride and stirred for 5 minutes. Stannic chloride (45 μl.) was added and the mixture stirred for 15 minutes. The mixture was poured into water, neutralized with ammonium hydroxide and extracted twice with chloroform. The extract was washed with water, dried over sodium sulfate, and concentrated to dryness. Trituration of the residue with 0.5 ml. of ethyl acetate and filtering gave 2-cyano-11H-pyrrolo[2,1-b][3]-benzazepin-11-one, m.p. 197° C.

Provenance & Evidence