Methanol → 9-formyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine

HRID 1763655Notes

Reaction equation

HRID 1763655 reaction equation
[C:1]([C:3]1[CH:22]=[CH:21][C:6]2[CH:7]=[CH:8][N:9]3[CH:20]=[CH:19][CH:18]=[C:10]3[C:11](=[CH:12][CH2:13][CH2:14][N:15]([CH3:17])[CH3:16])[C:5]=2[CH:4]=1)#N.C[OH:24]>>[CH:1]([C:3]1[CH:22]=[CH:21][C:6]2[CH:7]=[CH:8][N:9]3[CH:20]=[CH:19][CH:18]=[C:10]3[C:11](=[CH:12][CH2:13][CH2:14][N:15]([CH3:17])[CH3:16])[C:5]=2[CH:4]=1)=[O:24]

Participants

3

Reactant 2

HCID 887MethanolHCID 536970939-cyano-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine

Product 1

HCID 541503399-formyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine

Procedure

Similarly, by substituting 9-cyano-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine or its intermediate carbinol as starting material, there is produced 9-formyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine.

Sources & evidence

ORD record
ord-de913bd41c5f4189b16a25d2104e41c2
Source dataset
uspto-grants-1978_09
Patent number
US04112112

Reaction notes

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