HCID 54534525, compound → HCID 54400122, compound

HRID 1763657Notes

Reaction equation

HRID 1763657 reaction equation
[N+:1]([C:4]1[CH:23]=[CH:22][C:7]2[CH2:8][CH2:9][N:10]3[CH:21]=[CH:20][CH:19]=[C:11]3[C:12](=[CH:13][CH2:14][CH2:15][N:16]([CH3:18])[CH3:17])[C:6]=2[CH:5]=1)([O-])=O.[H][H]>[Pd].CO>[NH2:1][C:4]1[CH:23]=[CH:22][C:7]2[CH2:8][CH2:9][N:10]3[CH:21]=[CH:20][CH:19]=[C:11]3[C:12](=[CH:13][CH2:14][CH2:15][N:16]([CH3:18])[CH3:17])[C:6]=2[CH:5]=1

Participants

5

Reactant 2

HCID 54534525HCID 54534525, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 54400122HCID 54400122, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

A mixture of 9-nitro-11-(3-dimethylaminopropylidene)-6,11-dihydro-5H-pyrrolo[2,1-b][3]benzazepine (2.0 g.), 0.2 g. of 10% Pd/C and 350 ml. of methanol is hydrogenated until the theoretical amount of hydrogen is absorbed. The mixture is filtered and the filtrate is evaporated to dryness to yield 9-amino-11-(3-dimethylaminopropylidene)-6,11-dihydro-5H-pyrrolo[2,1-b][3]benzazepine.

Workup

  1. customis absorbed
  2. filtrationThe mixture is filtered
  3. customthe filtrate is evaporated to dryness

Sources & evidence

ORD record
ord-3cde720ab50d464fb16a7b92c5a5571d
Source dataset
uspto-grants-1978_09
Patent number
US04112112

Reaction notes

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