HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 2-carboxy-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Reactant | 2-carbamoyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine | HCID 70626901 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-carboxy-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine | HCID 54191185 | — |
Reaction Steps
To 2-carbamoyl-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine (0.112 moles) in 300 ml. of 50% sulfuric acid maintained at 50° C. is added slowly 25 g. of sodium nitrite in 75 ml. of water. At the end of the addition, the solid is filtered, washed with water and air-dried to yield 2-carboxy-11-(3-dimethylaminopropylidene)-11H-pyrrolo[2,1-b][3]benzazepine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04112112 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-eeb4aec01571413b890a75f0bf2ff792 |
| Source note | uspto-grants-1978_09 |