Methyl chloroacetate → Sodium 2-methoxy-2-oxoethane-1-sulfonate

Participants

Reaction Steps

A slurry of 217 g (2 mols) methyl chloroacetate and 252 g (2 mols) sodium sulfite in 500 ml water was stirred and heated under reflux for about 2 hours. The resulting solution was allowed to stand at about 25° C for 56 hours and then evaporated under reduced pressure to give solid residue. The residue was washed with acetone and dried under vacuum at 80°-90° C to give crude sodium methoxycarbonylmethylsulfonate salt.

Provenance & Evidence