HuagongsheHuagongshe Chemistry Print Report · For research reference only
n-(3-Aminopropyl)benzamide → 1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | n-(3-Aminopropyl)benzamide | HCID 238993 | — |
| Reactant | N-cyano-N'[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea | HCID 12889408 | — |
| Reactant | 1-nitro-2-methylthio-2-{2-[(4-methyl-1H-imidazol-5-yl)methylthio]ethylamino}ethylene | HCID 70456864 | — |
| Product | 1-[1(2-((5-Methyl-4-imidazolyl)methylthio)ethylamino)-2-nitrovinylamino]-3-[N'-cyano-N"-(2-(2-pyridylmethylthio)ethyl)guanidino]propane | HCID 178433675 | — |
Reaction Steps
1-Nitro-2-methylthio-2-[2-((5-methyl-4-imidazolyl)methylthio) ethylamino]ethylene was reacted with 3-benzoylaminopropylamine and the product was hydrolysed under acidic conditions and reacted with N-cyano-N'-[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea to give the title compound. EXAMPLE 29
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE029761 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-584d744885c945e79901d7caefb08fcf |
| Source note | uspto-grants-1978_09 |