Ethyl 3-(4-aminophenyl)propanoate → HCID 17341531, compound

HRID 1763921Notes

Reaction equation

HRID 1763921 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([O:12]CC)=[O:11])=[CH:4][CH:3]=1.[Cl:15][C:16]1[CH:17]=[CH:18][C:19]([O:25][CH3:26])=[C:20]([CH:24]=1)[C:21](Cl)=[O:22]>>[Cl:15][C:16]1[CH:17]=[CH:18][C:19]([O:25][CH3:26])=[C:20]([CH:24]=1)[C:21]([NH:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[CH:6][CH:7]=1)=[O:22]

Participants

3

Reactant 2

HCID 10442595Ethyl 3-(4-aminophenyl)propanoateHCID 123841765-Chloro-2-methoxybenzoyl chloride

Product 1

HCID 17341531HCID 17341531, compound

Procedure

By the reaction of ethyl β-(4-aminophenyl)-propionate hydrocholoride with 5-chloro-2-methoxybenzoyl chloride, there is obtained β-[4-(5-chloro-2-methoxybenzamido)-phenyl]-propionic acid; m.p. 188°-190° C., after recrystallization from ethanol.

Sources & evidence

ORD record
ord-a176fc936fd04955bc9eab5b85983771
Source dataset
uspto-grants-1978_09
Patent number
US04113871

Reaction notes

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