4-Chlorobenzoyl chloride → HCID 20304402, compound

HRID 1763932Notes

Reaction equation

HRID 1763932 reaction equation
Cl.[NH2:2][CH2:3][CH2:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([O:20]CC)=[O:19])=[CH:7][CH:6]=1.[Cl:23][C:24]1[CH:32]=[CH:31][C:27]([C:28](Cl)=[O:29])=[CH:26][CH:25]=1>>[Cl:23][C:24]1[CH:32]=[CH:31][C:27]([C:28]([NH:2][CH2:3][CH2:4][C:5]2[CH:6]=[CH:7][C:8]([CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][C:18]([OH:20])=[O:19])=[CH:9][CH:10]=2)=[O:29])=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 85014-Chlorobenzoyl chlorideHCID 20304363HCID 20304363, compound

Product 1

HCID 20304402HCID 20304402, compound

Procedure

By the reaction of ethyl 7-[4-(2-aminoethyl)-phenyl]-heptane-carboxylate hydrochloride with 4-chlorobenzoyl chloride, there is obtained 7-{4-[2-(4-chlorobenzamido)-ethyl]-phenyl}-heptane-carboxylic acid; m.p. 145°-148° C., after recrystallization from diethyl ether.

Sources & evidence

ORD record
ord-d749a97a26744e35a96d0332b28dbbe5
Source dataset
uspto-grants-1978_09
Patent number
US04113871

Reaction notes

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