HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl chloride → 2-Benzoyloxy-3-dimethylamino-1,1-diphenylpropane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl chloride | HCID 7412 | — |
| Reactant | 3-Dimethylamino-1,1-diphenyl-propan-2-ol | HCID 12549122 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 2-Benzoyloxy-3-dimethylamino-1,1-diphenylpropane | HCID 20309068 | 99% |
Reaction Steps
Benzoyl chloride (1 49g) was added to 3-dimethylamino-1,1-diphenyl-propan-2-ol (2,55g) in dry pyridine (10 ml.) and the solution allowed to stand for 4 hours. Pyridine was removed by evaporation and the residue dissolved in dilute hydrochloric acid and ether. Basification of the acid extract and isolation through ether in the usual manner gave 2-benzoyloxy-3-dimethylamino-1,1-diphenyl-propane (3.47g . 99%), m.p. 90°- 91°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04113972 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-1a3251c3c93c4e02a5306b116c3a94c8 |
| Source note | uspto-grants-1978_09 |