Potassium Hydroxide → Permethric acid

HRID 1763977Notes

Reaction equation

HRID 1763977 reaction equation
[CH3:1][C:2]1([CH3:14])[CH:4]([CH:5]=[C:6]([Cl:8])[Cl:7])[CH:3]1[C:9]([O:11]CC)=[O:10].[OH-].[K+]>CO>[CH3:1][C:2]1([CH3:14])[CH:4]([CH:5]=[C:6]([Cl:8])[Cl:7])[CH:3]1[C:9]([OH:11])=[O:10]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 101094Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, ethyl ester

Product 1

HCID 91658Permethric acid

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.80 Parts of ethyl 2,2-dimethyl-3-(2',2'-dichlorovinyl)-cyclopropane-carboxylate prepared in the same manner as in Example 1 was agitated at 40° to 50° C. for 3 hours in the presence of 8.65 parts of a 10% solution of potassium hydroxide and methanol to effect hydrolysis of the ester and obtain 1.43 parts of 2,2-dimethyl-3-(2',2'-dichlorovinyl)-cyclopropane-carboxylic acid, the data of the melting point and NMR spectrum of which were in agreement with the data described in Example 4.

Sources & evidence

ORD record
ord-a94196306be84a1a89e1a1fbf8bfcd27
Source dataset
uspto-grants-1978_09
Patent number
US04113968

Reaction notes

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