Acetic Acid → HCID 54243851, compound

Participants

Reaction Steps

The process for the preparation of this compound and its physical properties will be given below. 236.2 milligrams of the N-(o-hydroxycinnamyl)-isoindoline of the hereinafter-given Example 24 is dissolved in 10 milliliters of ethanol. After adding an ether solution of diazomethane thereto, the resulting mixture is left standing overnight at room temperature. The excess diazomethane is then decomposed with acetic acid, the solvent is distilled off, and the residue is recrystallized from acetone as a maleic acid salt to obtain 220.2 milligrams (yield 61.2%) of N-(o-methoxycinnamyl)-isoindoline.maleic acid salt as crystals having a melting point of 147°-148° C.

Provenance & Evidence