Oxalyl chloride → HCID 54077320, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of 12 g of the sodium salt of α-[p-(1-cyclohexenyl)-phenoxy]-heptanoic acid in 200 ml of absolute benzene are added with stirring at 5°C 25 g of oxalyl chloride. The mixture is continuously stirred overnight at room temperature, then evaporated to dryness in vacuo. The residue is dissolved in 200 ml of absolute benzene are added with stirring at 5° C 25 g of oxalyl chloride. The mixture is continuously stirred overnight at room temperature, then evaporated to dryness in vacuo. The residue is dissolved in 200 ml of absolute benzene and filtered under anhydrous conditions. The filtrate is evaporated to dryness in vacuo. The residue yields the crude α-[p-(1-cyclohexenyl)-phenoxy]-heptanoic acid chloride, which is used directly for further processing.

Provenance & Evidence