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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764235Generated: October 27, 2026

1-Fluoro-4-methoxy-2-nitrobenzene → Methyl 5-ethyl-2-(4-methoxy-2-nitroanilino)-thiophene-3-carboxylate

https://huagongshe.com/reaction/1764235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Fluoro-4-methoxy-2-nitrobenzeneHCID 565653—
Reactant2-Amino-5-ethyl-3-thiophenecarboxylic acid methyl esterHCID 737094—
SolventEthanolHCID 702—
ProductMethyl 5-ethyl-2-(4-methoxy-2-nitroanilino)-thiophene-3-carboxylateHCID 12438954—

Reaction Steps

2-Fluoro-5-methoxy-nitrobenzene and methyl 2-amino-5-ethyl-thiophene-3-carboxylate, m.p. 125°-127° C. (EtOH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04115568
Source datasetuspto-grants-1978_09
ORD IDord-7c400e16a6354bac89c963b260da1718
Source noteuspto-grants-1978_09