HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride, 2-(2-chlorophenyl)- → 2-Phenyl-3,4-dihydro-2H-1,4-benzoxazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride, 2-(2-chlorophenyl)- | HCID 182669 | — |
| Reactant | 3,4-Dihydro-2H-1,4-benzoxazine | HCID 585096 | — |
| Reactant | O-Phenylhydroxylamine | HCID 2794249 | — |
| Product | 2-Phenyl-3,4-dihydro-2H-1,4-benzoxazine | HCID 13790491 | — |
Reaction Steps
By a procedure similar to that described for the synthesis of 3,4-dihydro-2H-1,4-benzoxazine (Example 142), O-aminophenol and 2-chlorophenylacetyl chloride produces 3,4-dihydro-2-phenyl-2H-1,4-benzoxazine, m.p. 113°-116° which, according to the reaction scheme of Example 110 is converted to the title compound, m.p. 311°-313° .
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04115577 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-55bd5f9b727f4cdba6c52655b0178137 |
| Source note | uspto-grants-1978_09 |