1-Fluoro-4-methoxy-2-nitrobenzene → Methyl 5-ethyl-2-(4-methoxy-2-nitroanilino)-thiophene-3-carboxylate

HRID 1764272Notes

Reaction equation

HRID 1764272 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11].[NH2:13][C:14]1[S:15][C:16]([CH2:23][CH3:24])=[CH:17][C:18]=1[C:19]([O:21][CH3:22])=[O:20]>CCO>[CH2:23]([C:16]1[S:15][C:14]([NH:13][C:2]2[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][C:3]=2[N+:10]([O-:12])=[O:11])=[C:18]([C:19]([O:21][CH3:22])=[O:20])[CH:17]=1)[CH3:24]

Participants

4

Reactant 2

HCID 5656531-Fluoro-4-methoxy-2-nitrobenzeneHCID 7370942-Amino-5-ethyl-3-thiophenecarboxylic acid methyl ester

Product 1

HCID 12438954Methyl 5-ethyl-2-(4-methoxy-2-nitroanilino)-thiophene-3-carboxylate

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

2-Fluoro-5-methoxy-nitrobenzene and methyl 2-amino-5-ethyl-thiophene-3-carboxylate, m.p. 125°-127° C. (EtOH).

Sources & evidence

ORD record
ord-0069190c4158436485425ca77b61ea6e
Source dataset
uspto-grants-1978_09
Patent number
US04115574

Reaction notes

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