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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764273Generated: November 1, 2026

2,5-Difluoronitrobenzene → Ethyl 2-(4-fluoro-2-nitroanilino)-thiophene-3-carboxylate

https://huagongshe.com/reaction/1764273

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DifluoronitrobenzeneHCID 67767—
ReactantEthyl 2-aminothiophene-3-carboxylateHCID 1988156—
SolventEthanolHCID 702—
ProductEthyl 2-(4-fluoro-2-nitroanilino)-thiophene-3-carboxylateHCID 20387707—

Reaction Steps

2,5-Difluoro-nitrobenzene and ethyl 2-amino-thiophene-3-carboxylate, m.p. 125° C. (EtOH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04115574
Source datasetuspto-grants-1978_09
ORD IDord-51c2791b8fc54b2aaca8ed5de49f74f0
Source noteuspto-grants-1978_09