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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1764276Generated: November 1, 2026

Ethyl 2-amino-5-ethyl-3-thenoate → Ethyl 5-ethyl-2-(2-trifluoromethyl-6-nitroanilino)-thiophene-3-carboxylate

https://huagongshe.com/reaction/1764276

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 2-amino-5-ethyl-3-thenoateHCID 78263—
Reactant2-Fluoro-3-nitrobenzotrifluorideHCID 23340645—
SolventEthanolHCID 702—
ProductEthyl 5-ethyl-2-(2-trifluoromethyl-6-nitroanilino)-thiophene-3-carboxylateHCID 20387731—

Reaction Steps

Ethyl 2-amino-5-ethylthiophene-3-carboxylate and 2-fluoro-3-trifluoromethylnitrobenzene, m.p. 72°-73° C. (EtOH).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04115574
Source datasetuspto-grants-1978_09
ORD IDord-ee7ca3fdcfae409c8189b4c5ae707697
Source noteuspto-grants-1978_09