HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Norbornene → Methyl 4-(2-aminoanilino)thiophene-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Norbornene | HCID 10352 | — |
| Reactant | Methyl 4-(2-aminoanilino)-2,5-dihydrothiophene-3-carboxylate | HCID 2819686 | — |
| Reactant | Norborna-diene | HCID 18006658 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Cyclohexene | HCID 8079 | — |
| Product | Methyl 4-(2-aminoanilino)thiophene-3-carboxylate | HCID 12658694 | — |
Reaction Steps
Methyl 3-(2-aminoanilino)-2,5-dihydrothiophene-4-carboxylate (2.5 g, 0.001 mol) was added to a flask containing palladium on charcoal catalyst (5%, 200 mg) in cyclohexene (or norbornadiene or norbornylene) (50 ml) and the reaction was heated at reflux with stirring for 4 hours, the reaction being followed by t.l.c.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04115574 |
| Source dataset | uspto-grants-1978_09 |
| ORD ID | ord-e6321cf8d8fc4077adda7bce67ed3c13 |
| Source note | uspto-grants-1978_09 |