Potassium Bromide → HCID 178431927, compound

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Reaction Steps

The title compound is prepared in 64% yield from 2-(2-[2-aminoethoxy]phenyl)acetic acid (U.S. Pat No. 3,759,905) and 6-amino-2,2-dimethyl-3-(5-tetrazolyl)penam, by a procedure analogous to that of Example LXXXV. IR (KBr disc): 1780 cm-1 (β-lactam) and 1667 cm-1 (amide I). NMR (in D2O: 7.1 ppm (m,4H), 5.7 ppm (d,1H), 5.5 ppm (d,1H), 5.2 ppm (s,1H), 3.7-3.3 ppm (m,4H), 3.1 ppm (q,12H), 1.6 ppm (s,3H), 1.2 ppm (t,18H), 1.0 ppm (s,3H). The product is a 1:2 complex of the title compound and triethylamine.

Provenance & Evidence