Hydrochloric Acid → HCID 54675792, compound

Participants

Reaction Steps

Phenylisocyanate (20.5 mmol) was added to a cooled DMF solution (25 ml) containing 20.5 mmol of NaH and 5.0 g (18.3 mmol) of 4-hydroxy-8-phenyl-1,2-benzoxathiin-2,2-dioxide. The resultant mixture was heated at 75° for 2.5 hours. The mixture was cooled, poured into ice-H2O (100 ml) and acidified with HCl. The resultant precipitate was collected by filtration and gave 6.70 g (93.3%) of the expected product, mp. 175°. The crude product was purified by recrystallization from 2-PrOH/hexane to give the analytical sample, mp. 181°-183°.

Provenance & Evidence