4-Aminophenylacetic acid → HCID 16787059, compound

HRID 1764493Notes

Reaction equation

HRID 1764493 reaction equation
[CH:1]12[C:10](=[O:11])[O:9][C:7](=O)[CH:2]1[CH2:3][CH2:4][CH2:5][CH2:6]2.[NH2:12][C:13]1[CH:18]=[CH:17][C:16]([CH2:19][C:20]([OH:22])=[O:21])=[CH:15][CH:14]=1>>[O:9]=[C:7]1[CH:2]2[CH:1]([CH2:6][CH2:5][CH2:4][CH2:3]2)[C:10](=[O:11])[N:12]1[C:13]1[CH:14]=[CH:15][C:16]([CH2:19][C:20]([OH:22])=[O:21])=[CH:17][CH:18]=1

Participants

3

Reactant 2

HCID 145334-Aminophenylacetic acidHCID 85689Hexahydrophthalic anhydride

Product 1

HCID 16787059HCID 16787059, compound

Procedure

Equimolar amounts of cyclohexane-1,2-dicarboxylic acid anhydride and p-aminophenylacetic acid were reacted as described in step (a) of Example 1, yielding quantitatively 4-(1,3-dioxo-hexahydro-2-isoindolinyl)phenylacetic acid (melting point 219°-221° C.).

Sources & evidence

ORD record
ord-c235a49d056d4c9b97eb4acc1bb70b09
Source dataset
uspto-grants-1978_09
Patent number
US04116972

Reaction notes

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