Sodium Phosphate, Dibasic → Hydrogen Peroxide

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Reaction Steps

2.54 g (10 mmoles) of (1,2,3,5/0)-1,2-anhydro-3,6-dibromo-cyclohex-4-ene-1,2-diol are dissolved in 50 ml of methylene chloride, 5.68 g (40 mmoles) of finely powdered disodium phosphate are added, followed by 15 mmoles of trifluoroperacetic acid added whilst cooling with ice, and the mixture is stirred for 24 hours at 0°-10° C. (Trifluoroperacetic acid is obtained from bis-trifluoroacetic anhydride and 85 percent strength hydrogen peroxide). The solvent is stripped off and the entire residue is thoroughly washed with water, dried and recrystallized from dioxane. 2.2 g (82%) of colorless needles, melting point 225°-227° C., are obtained.

Provenance & Evidence