1-(2-Chloroethyl)piperidine → HCID 20381771, compound

HRID 1764628Notes

Reaction equation

HRID 1764628 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]2[NH:8][C:9]3[C:15](=[O:16])[N:14]([CH3:17])[C:13]4[CH:18]=[CH:19][CH:20]=[CH:21][C:12]=4[O:11][C:10]=3[C:5]2=[CH:4][CH:3]=1.[N:22]1([CH2:28][CH2:29]Cl)[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[Cl:1][C:2]1[CH:7]=[C:6]2[N:8]([CH2:29][CH2:28][N:22]3[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]3)[C:9]3[C:15](=[O:16])[N:14]([CH3:17])[C:13]4[CH:18]=[CH:19][CH:20]=[CH:21][C:12]=4[O:11][C:10]=3[C:5]2=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 748271-(2-Chloroethyl)piperidineHCID 20381773HCID 20381773, compound

Product 1

HCID 20381771HCID 20381771, compound

Procedure

In the same way as described in example 19, 3-chloro-7-methyl-7H-indolo[3,2-b][1,5]benzoxazepin-6(5H)-one was alkylated with piperidinoethyl chloride. The crude solid base was recrystallized from acetonitrile, mp. 160°-162°.

Workup

  1. customThe crude solid base was recrystallized from acetonitrile, mp. 160°-162°

Sources & evidence

ORD record
ord-a5eb134acaf44f67914efa7b6165c537
Source dataset
uspto-grants-1978_09
Patent number
US04117129

Reaction notes

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