Diethyl (ethoxymethylene)malonate → HCID 12736933, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 2-aminochromone (3.22 g, 0.02 mole) and diethyl ethoxymethylenemalonate (8.64 g, 0.04 mole) is heated at 130° C. under nitrogen until an homogeneous solution forms (16 hrs.). The reaction mixture is cooled. The product, which precipitated, is filtered off and washed with hexane. Recrystallization from ethylacetate gives pale yellow crystals (6.01 g, 91%), mp 138°-140° C.

Provenance & Evidence