HCID 12736933, compound → HCID 12736934, compound

Participants

Reaction Steps

Diethyl {[(4-oxo-4H-1-benzopyran-2-yl)amino]methylene}malonate (36 g, 0.11 mole) is added to diphenyl ether (300 ml) at 200° C. The reaction mixture is refluxed under nitrogen for 90 min. The product, which crystallized out on cooling, is filtered off and washed with ethyl acetate. Recrystallization from DMF gives white crystals (25.6 g, 83%), mp 174°-175° C.

Provenance & Evidence