Acetyl chloride → HCID 12726827, compound

HRID 1764656Notes

Reaction equation

HRID 1764656 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[CH2:9][CH2:10][C:11](=O)[NH:12][N:13]=2)[CH:5]=[CH:6][CH:7]=1.ClC1C=C(C2[N:27]=[N:26][C:25](NN)=[CH:24]C=2)C=CC=1.C(Cl)(=O)C>>[CH3:24][C:25]1[N:12]2[N:13]=[C:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=3)[CH:9]=[CH:10][C:11]2=[N:27][N:26]=1

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 133889093-(3-Chlorophenyl)-6-hydrazinylpyridazineHCID 22768943HCID 22768943, compound

Product 1

HCID 12726827HCID 12726827, compound

Procedure

Following the general procedure of Example 12, 6-(m-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone is converted to 6-(m-chlorophenyl)-3-hydrazinopyridazine which is treated with acetyl chloride to give the title compound, m.p. 165°-167° C.

Sources & evidence

ORD record
ord-afd2846045bc4b05b00fcaaa4d9a2dea
Source dataset
uspto-grants-1978_09
Patent number
US04117130

Reaction notes

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